NDA Partners LLC: A Development Partner to Biopharmaceutical Investors and Companies

Nick Holford, MB, ChB, FRACP, FISoP, FAAPS

Practice Area Focus

  • Drugs
  • Clinical Pharmacology
  • Clinical Trial Simulation
  • PKPD
  • Disease Progression
  • Time to Event


Nick Holford joined NDA Partners as an Expert Consultant in 2013. He is an expert in clinical pharmacology, PKPD, and clinical trial simulation.

Dr. Holford is currently Professor of Clinical Pharmacology in the Department of Pharmacology and Clinical Pharmacology, University of Auckland, New Zealand and Honorary Professor of Clinical Pharmacology at University of California, San Francisco. He was previously a Specialist in Internal Medicine at Auckland Hospital and Associate Professor at the University of Auckland and Georgetown University.

Dr. Holford’s research interests include population PKPD analyses of clinical trials of drugs, the quantitative aspects of clinical pharmacology, and pharmacokinetic-dynamic analysis software. His current focus is on the development of disease progress models for understanding clinical pharmacology, understanding the principles guiding doses in babies, children and adults, and the application of target concentration intervention for individual care of patients.